DDAVP in Bleeding Disorders

Desmopressin (DDAVP) in the treatment of bleeding disorders: the first 20 years.

I the enhancement of blood clotting associated with stress was caused by the liberation of adrenaline in plasma. In 1957, N 1977 DESMOPRESSIN (1-deamino-8-D-arginine vasopressin, abbreviated DDAVP), a derivative of the antidiuretic hormone, was used for the first time to treat patients a possible mechanism for faster clotting after adrenaline was provided by Marciniak, who found a transient inc...

Hyponatremia after desmopressin (DDAVP) use in pediatric patients with bleeding disorders undergoing surgeries.

Desmopressin (DDAVP) 1-deamino-8-D-arginine vasopressin is used in patients with bleeding disorders, including mild factor VIII deficiency, types 1 and 2 von Willebrand disease, and platelet function defects, undergoing surgeries to help control bleeding. We conducted a retrospective chart review of bleeding disorder patients undergoing inpatient surgery at Toledo Children's Hospital, OH, from ...

Low-dose intranasal desmopressin (DDAVP) for uremic bleeding.

Bleeding Disorders in Animals

Bleeding Disorders

Bleeding disorders are usually taken to mean coagulopathies with reduced clotting of the blood but also encompass disorders characterised by abnormal platelet function or blood vessel walls that result in increased bleeding. Bleeding disorders may result from faults at many different levels in the coagulation process. They can range from severe and life-threatening conditions, such as haemophil...